diff --git a/packages/grafana-ui/src/components/Table/TableNG/TableNG.tsx b/packages/grafana-ui/src/components/Table/TableNG/TableNG.tsx
index c45a44eac8d..3b87798c3e7 100644
--- a/packages/grafana-ui/src/components/Table/TableNG/TableNG.tsx
+++ b/packages/grafana-ui/src/components/Table/TableNG/TableNG.tsx
@@ -97,6 +97,7 @@ import {
   withDataLinksActionsTooltip,
   getSummaryCellTextAlign,
   parseStyleJson,
+  IS_SAFARI_26,
 } from './utils';
 
 const EXPANDED_COLUMN_KEY = 'expanded';
@@ -287,7 +288,7 @@ export function TableNG(props: TableNGProps) {
   const commonDataGridProps = useMemo(
     () =>
       ({
-        enableVirtualization: enableVirtualization !== false && rowHeight !== 'auto',
+        enableVirtualization: !IS_SAFARI_26 && enableVirtualization !== false && rowHeight !== 'auto',
         defaultColumnOptions: {
           minWidth: 50,
           resizable: true,
@@ -460,7 +461,8 @@ export function TableNG(props: TableNGProps) {
           ? clsx('table-cell-actions', getCellActionStyles(theme, textAlign))
           : undefined;
 
-        const shouldOverflow = rowHeight !== 'auto' && (shouldTextOverflow(field) || Boolean(maxRowHeight));
+        const shouldOverflow =
+          !IS_SAFARI_26 && rowHeight !== 'auto' && (shouldTextOverflow(field) || Boolean(maxRowHeight));
         const textWrap = rowHeight === 'auto' || shouldTextWrap(field);
         const withTooltip = withDataLinksActionsTooltip(field, cellType);
         const canBeColorized = canFieldBeColorized(cellType, applyToRowBgFn);
diff --git a/packages/grafana-ui/src/components/Table/TableNG/hooks.ts b/packages/grafana-ui/src/components/Table/TableNG/hooks.ts
index cc648af019a..83c320dacbf 100644
--- a/packages/grafana-ui/src/components/Table/TableNG/hooks.ts
+++ b/packages/grafana-ui/src/components/Table/TableNG/hooks.ts
@@ -16,6 +16,7 @@ import {
   computeColWidths,
   buildHeaderHeightMeasurers,
   buildCellHeightMeasurers,
+  IS_SAFARI_26,
 } from './utils';
 
 // Helper function to get displayed value
@@ -468,7 +469,7 @@ export function useScrollbarWidth(ref: RefObject<DataGridHandle>, height: number
   useLayoutEffect(() => {
     const el = ref.current?.element;
 
-    if (!el) {
+    if (!el || IS_SAFARI_26) {
       return;
     }
 
diff --git a/packages/grafana-ui/src/components/Table/TableNG/styles.ts b/packages/grafana-ui/src/components/Table/TableNG/styles.ts
index feb5e650d90..09076724b20 100644
--- a/packages/grafana-ui/src/components/Table/TableNG/styles.ts
+++ b/packages/grafana-ui/src/components/Table/TableNG/styles.ts
@@ -1,11 +1,12 @@
 import { css } from '@emotion/css';
 import { Property } from 'csstype';
+import memoize from 'micro-memoize';
 
 import { GrafanaTheme2, colorManipulator } from '@grafana/data';
 
 import { COLUMN, TABLE } from './constants';
 import { TableCellStyles } from './types';
-import { getJustifyContent, TextAlign } from './utils';
+import { getJustifyContent, IS_SAFARI_26, TextAlign } from './utils';
 
 export const getGridStyles = (theme: GrafanaTheme2, enablePagination?: boolean, transparent?: boolean) => {
   const bgColor = transparent ? theme.colors.background.canvas : theme.colors.background.primary;
@@ -51,14 +52,14 @@ export const getGridStyles = (theme: GrafanaTheme2, enablePagination?: boolean,
       '& > :not(.rdg-summary-row, .rdg-header-row) > .rdg-cell': {
         [getActiveCellSelector()]: { boxShadow: theme.shadows.z2 },
         // selected cells should appear below hovered cells.
-        '&:hover': { zIndex: theme.zIndex.tooltip - 7 },
+        ...(!IS_SAFARI_26 && { '&:hover': { zIndex: theme.zIndex.tooltip - 7 } }),
         '&[aria-selected=true]': { zIndex: theme.zIndex.tooltip - 6 },
       },
 
       '.rdg-cell.rdg-cell-frozen': {
-        backgroundColor: '--rdg-row-background-color',
+        backgroundColor: 'var(--rdg-row-background-color)',
         zIndex: theme.zIndex.tooltip - 4,
-        '&:hover': { zIndex: theme.zIndex.tooltip - 2 },
+        ...(!IS_SAFARI_26 && { '&:hover': { zIndex: theme.zIndex.tooltip - 2 } }),
         '&[aria-selected=true]': { zIndex: theme.zIndex.tooltip - 3 },
       },
 
@@ -70,7 +71,6 @@ export const getGridStyles = (theme: GrafanaTheme2, enablePagination?: boolean,
           },
         },
       },
-
       '.rdg-summary-row >': {
         '.rdg-cell': {
           // 0.75 padding causes "jumping" on hover.
@@ -232,5 +232,22 @@ export const getTooltipStyles = (theme: GrafanaTheme2, textAlign: TextAlign) =>
   }),
 });
 
-export const getActiveCellSelector = (isNested?: boolean) =>
-  isNested ? '.rdg-cell:hover &, [aria-selected=true] &' : '&:hover, &[aria-selected=true]';
+const ACTIVE_CELL_SELECTORS = {
+  hover: {
+    nested: '.rdg-cell:hover &',
+    normal: '&:hover',
+  },
+  selected: {
+    nested: '[aria-selected=true] &',
+    normal: '&[aria-selected=true]',
+  },
+} as const;
+
+export const getActiveCellSelector = memoize((isNested?: boolean) => {
+  const selectors = [];
+  selectors.push(ACTIVE_CELL_SELECTORS.selected[isNested ? 'nested' : 'normal']);
+  if (!IS_SAFARI_26) {
+    selectors.push(ACTIVE_CELL_SELECTORS.hover[isNested ? 'nested' : 'normal']);
+  }
+  return selectors.join(', ');
+});
diff --git a/packages/grafana-ui/src/components/Table/TableNG/utils.ts b/packages/grafana-ui/src/components/Table/TableNG/utils.ts
index a133fe883b0..848f21957b0 100644
--- a/packages/grafana-ui/src/components/Table/TableNG/utils.ts
+++ b/packages/grafana-ui/src/components/Table/TableNG/utils.ts
@@ -1029,3 +1029,13 @@ export function parseStyleJson(rawValue: unknown): CSSProperties | void {
     }
   }
 }
+
+// Safari 26 introduced rendering bugs which require us to disable several features of the table.
+export const IS_SAFARI_26 = (() => {
+  if (navigator == null) {
+    return false;
+  }
+  const userAgent = navigator.userAgent;
+  const safariVersionMatch = userAgent.match(/Version\/(\d+)\./);
+  return safariVersionMatch && parseInt(safariVersionMatch[1], 10) === 26;
+})();